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1

Multilayered Genetic and Omics Dissection of Mitochondrial Activity in a Mouse Reference Population

Wu, Yibo, Williams, Evan G., Dubuis, Sébastien, Mottis, Adrienne, Jovaisaite, Virginija, Houten, Sander M., Argmann, Carmen A., Faridi, Pouya, Wolski, Witold, Kutalik, Zoltán, Zamboni, Nicola, Auwerx,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.67 MB

english, 2014

2

Peroxisome proliferator-activated receptor γ: the more the merrier?

C. A. Argmann, T.-A. Cock, J. Auwerx

Journal:

European Journal of Clinical Investigation

Year:

2005

Language:

english

File:

PDF, 177 KB

english, 2005

3

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Marie Lagouge, Carmen Argmann, Zachary Gerhart-Hines, Hamid Meziane, Carles Lerin, Frederic Daussin, Nadia Messadeq, Jill Milne, Philip Lambert, Peter Elliott, Bernard Geny, Markku Laakso, Pere Puigse

Journal:

Year:

2006

Language:

english

File:

PDF, 1.81 MB

english, 2006

4

PPARγ in human and mouse physiology

Sami Heikkinen, Johan Auwerx, Carmen A. Argmann

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2007

Language:

english

File:

PDF, 377 KB

english, 2007

5

HUMAN ARTERIAL SMOOTH MUSCLE CELL SUB-POPULATIONS ARE DIFFERENTIALLY CONVERTED ITNO FOAM CELLS BY NATIVE AND OXIDIZED LIPOPROTEINS

Carmen A. Argmann, Cynthia G. Sawyez, Shaohua LI, Robert A Hegele, J.Geoffrey Pickering, Murray W. Huff

Journal:

Cardiovascular Pathology

Year:

2004

Language:

english

File:

PDF, 41 KB

english, 2004

6

Insulin Secretion: SIRT4 Gets in on the Act

Carmen Argmann, Johan Auwerx

Journal:

Year:

2006

Language:

english

File:

PDF, 272 KB

english, 2006

7

New Driver for Lipid Synthesis

Sander M. Houten, Carmen A. Argmann

Journal:

Year:

2011

Language:

english

File:

PDF, 380 KB

english, 2011

8

Mouse phenogenomics: The fast track to “systems metabolism”

Carmen A. Argmann, Pierre Chambon, Johan Auwerx

Journal:

Cell Metabolism

Year:

2005

Language:

english

File:

PDF, 519 KB

english, 2005

9

The Pro12Ala PPARγ2 Variant Determines Metabolism at the Gene-Environment Interface

Sami Heikkinen, Carmen Argmann, Jérôme N. Feige, Hana Koutnikova, Marie-France Champy, Nassim Dali-Youcef, Eric E. Schadt, Markku Laakso, Johan Auwerx

Journal:

Cell Metabolism

Year:

2009

Language:

english

File:

PDF, 1.60 MB

english, 2009

10

Impaired amino acid metabolism contributes to fasting-induced hypoglycemia in fatty acid oxidation defects

Houten, S. M., Herrema, H., te Brinke, H., Denis, S., Ruiter, J. P. N., van Dijk, T. H., Argmann, C. A., Ottenhoff, R., Muller, M., Groen, A. K., Kuipers, F., Reijngoud, D.-J., Wanders, R. J. A.

Journal:

Human Molecular Genetics

Year:

2013

Language:

english

File:

PDF, 1.16 MB

english, 2013

11

Identification and characterization of Eci3, a murine kidney-specific 3, 2-enoyl-CoA isomerase

van Weeghel, M., Ofman, R., Argmann, C. A., Ruiter, J. P. N., Claessen, N., Oussoren, S. V., Wanders, R. J. A., Aten, J., Houten, S. M.

Journal:

The FASEB Journal

Year:

2014

Language:

english

File:

PDF, 1.55 MB

english, 2014

12

Lysosomal Stress in Obese Adipose Tissue Macrophages Contributes to MITF-Dependent Gpnmb Induction

Gabriel, T. L., Tol, M. J., Ottenhof, R., van Roomen, C., Aten, J., Claessen, N., Hooibrink, B., de Weijer, B., Serlie, M. J., Argmann, C., van Elsenburg, L., Aerts, J. M. F. G., van Eijk, M.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.03 MB

english, 2014

13

A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility

Keller, M. P., Choi, Y., Wang, P., Belt Davis, D., Rabaglia, M. E., Oler, A. T., Stapleton, D. S., Argmann, C., Schueler, K. L., Edwards, S., Steinberg, H. A., Chaibub Neto, E., Kleinhanz, R., Turner,

Journal:

Genome Research

Year:

2008

Language:

english

File:

PDF, 909 KB

english, 2008

14

Regulation of Macrophage Cholesterol Efflux through Hydroxymethylglutaryl-CoA Reductase Inhibition: A ROLE FOR RhoA IN ABCA1-MEDIATED CHOLESTEROL EFFLUX

Argmann, C. A., Edwards, J. Y., Sawyez, C. G., O'Neil, C. H., Hegele, R. A., Pickering, J. G., Huff, M. W.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 1.08 MB

english, 2005

15

The metabolic footprint of aging in mice

Houtkooper, Riekelt H., Argmann, Carmen, Houten, Sander M., Cantó, Carles, Jeninga, Ellen H., Andreux, Pénélope A., Thomas, Charles, Doenlen, Raphaël, Schoonjans, Kristina, Auwerx, Johan

Journal:

Scientific Reports

Year:

2011

Language:

english

File:

PDF, 2.53 MB

english, 2011

16

Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network

Tu, Z., Argmann, C., Wong, K. K., Mitnaul, L. J., Edwards, S., Sach, I. C., Zhu, J., Schadt, E. E.

Journal:

Genome Research

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

17

Compromised Intestinal Lipid Absorption in Mice with a Liver-Specific Deficiency of Liver Receptor Homolog 1

Mataki, C., Magnier, B. C., Houten, S. M., Annicotte, J.-S., Argmann, C., Thomas, C., Overmars, H., Kulik, W., Metzger, D., Auwerx, J., Schoonjans, K.

Journal:

Molecular and Cellular Biology

Year:

2007

Language:

english

File:

PDF, 901 KB

english, 2007

18

PS13 - 2. Glycoprotein Nonmetastatic Melanoma protein B (GPNMB) is induced in obese macrophages as a result of lysosomal stress

Lizama, Tanit, Tol, Marc, Ottenhof, Roelof, van Roomen, Cindy, Aten, Jan, Claessen, Nike, Hooibrink, Berend, de Weijer, Barbara, Serlie, Mireille J., Argmann, Carmen, van Elsenburg, Leonie, Aerts, Joh

Journal:

Nederlands Tijdschrift voor Diabetologie

Year:

2013

Language:

english

File:

PDF, 227 KB

english, 2013

19

Activation of Peroxisome Proliferator-Activated Receptor Gamma and Retinoid X Receptor Results in Net Depletion of Cellular Cholesteryl Esters in Macrophages Exposed to Oxidized Lipoproteins

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2003

Language:

english

File:

PDF, 701 KB

english, 2003

20

Peroxisomal L-bifunctional enzyme (Ehhadh) is essential for the production of medium-chain dicarboxylic acids

Houten, S. M., Denis, S., Argmann, C. A., Jia, Y., Ferdinandusse, S., Reddy, J. K., Wanders, R. J. A.

Journal:

The Journal of Lipid Research

Year:

2012

Language:

english

File:

PDF, 1.19 MB

english, 2012

21

Human Smooth Muscle Cell Subpopulations Differentially Accumulate Cholesteryl Ester When Exposed to Native and Oxidized Lipoproteins

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2004

Language:

english

File:

PDF, 285 KB

english, 2004

22

Transforming Growth Factor- 1 Inhibits Macrophage Cholesteryl Ester Accumulation Induced by Native and Oxidized VLDL Remnants

Argmann, C. A., Van Den Diepstraten, C. H., Sawyez, C. G., Edwards, J. Y., Hegele, R. A., Wolfe, B. M., Huff, M. W.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2001

Language:

english

File:

PDF, 115 KB

english, 2001

23

Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPD

Yoo, Seungyeul, Takikawa, Sachiko, Geraghty, Patrick, Argmann, Carmen, Campbell, Joshua, Lin, Luan, Huang, Tao, Tu, Zhidong, Feronjy, Robert, Spira, Avrum, Schadt, Eric E., Powell, Charles A., Zhu, Ju

Journal:

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

24

Pparγ2 Is a Key Driver of Longevity in the Mouse

Argmann, Carmen, Dobrin, Radu, Heikkinen, Sami, Auburtin, Aurélie, Pouilly, Laurent, Cock, Terrie-Anne, Koutnikova, Hana, Zhu, Jun, Schadt, Eric E., Auwerx, Johan, Barsh, Gregory S.

Journal:

Year:

2009

Language:

english

File:

PDF, 280 KB

english, 2009

25

A Next Generation Multiscale View of Inborn Errors of Metabolism

Argmann, Carmen A., Houten, Sander M., Zhu, Jun, Schadt, Eric E.

Journal:

Cell Metabolism

Year:

2015

Language:

english

File:

PDF, 2.68 MB

english, 2015

26

Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance

Hamers, Anouk A. J., Argmann, Carmen, Moerland, Perry D., Koenis, Duco S., Marinković, Goran, Sokolović, Milka, de Vos, Alex F., de Vries, Carlie J. M., van Tiel, Claudia M.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

27

Systems proteomics of liver mitochondria function

Williams, E. G., Wu, Y., Jha, P., Dubuis, S., Blattmann, P., Argmann, C. A., Houten, S. M., Amariuta, T., Wolski, W., Zamboni, N., Aebersold, R., Auwerx, J.

Journal:

Year:

2016

Language:

english

File:

PDF, 6.50 MB

english, 2016

28

Inter-tissue coexpression network analysis reveals DPP4 as an important gene in heart to blood communication

Long, Quan, Argmann, Carmen, Houten, Sander M., Huang, Tao, Peng, Siwu, Zhao, Yong, Tu, Zhidong, Zhu, Jun

Journal:

Genome Medicine

Year:

2016

Language:

english

File:

PDF, 3.00 MB

english, 2016

29

Blood and Intestine eQTLs from an Anti-TNF-Resistant Crohn's Disease Cohort Inform IBD Genetic Association Loci

Di Narzo, Antonio F, Peters, Lauren A, Argmann, Carmen, Stojmirovic, Aleksandar, Perrigoue, Jacqueline, Li, Katherine, Telesco, Shannon, Kidd, Brian, Walker, Jennifer, Dudley, Joel, Cho, Judy, Schadt,

Journal:

Clinical and Translational Gastroenterology

Year:

2016

Language:

english

File:

PDF, 2.51 MB

english, 2016

30

Impact of obesity on taste receptor expression in extra-oral tissues: emphasis on hypothalamus and brainstem

Herrera Moro Chao, D., Argmann, C., Van Eijk, M., Boot, R. G., Ottenhoff, R., Van Roomen, C., Foppen, E., Siljee, J. E., Unmehopa, U. A., Kalsbeek, A., Aerts, J. M. F. G.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.98 MB

english, 2016

31

Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

Yang, Jialiang, Huang, Tao, Petralia, Francesca, Long, Quan, Zhang, Bin, Argmann, Carmen, Zhao, Yong, Mobbs, Charles V., Schadt, Eric E., Zhu, Jun, Tu, Zhidong, Ardlie, Kristin G., Deluca, David S., S

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.69 MB

english, 2015

32

Erratum: Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

Yang, Jialiang, Huang, Tao, Petralia, Francesca, Long, Quan, Zhang, Bin, Argmann, Carmen, Zhao, Yong, Mobbs, Charles V., Schadt, Eric E., Zhu, Jun, Tu, Zhidong

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 108 KB

english, 2016

33

DNA methylation alters transcriptional rates of differentially expressed genes and contributes to pathophysiology in mice fed a high fat diet

Zhang, Pili, Chu, Tianjiao, Dedousis, N., Mantell, Benjamin S., Sipula, Ian, Li, Lucy, Bunce, Kimberly D., Shaw, Patricia A., Katz, Liora S., Zhu, Jun, Argmann, Carmen, O'Doherty, Robert M., Peters, D

Journal:

Molecular Metabolism

Year:

2017

Language:

english

File:

PDF, 2.87 MB

english, 2017

34

Acute detachment of hexokinase II from mitochondria modestly increases oxygen consumption of the intact mouse heart

Nederlof, Rianne, Denis, Simone, Lauzier, Benjamin, Rosiers, Christine Des, Laakso, Markku, Hagen, Jacob, Argmann, Carmen, Wanders, Ronald, Houtkooper, Riekelt H., Hollmann, Markus W., Houten, Sander

Journal:

Year:

2017

Language:

english

File:

PDF, 420 KB

english, 2017

35

Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice

Argmann, Carmen A., Violante, Sara, Dodatko, Tetyana, Amaro, Mariana P., Hagen, Jacob, Gillespie, Virginia L., Buettner, Christoph, Schadt, Eric E., Houten, Sander M.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

36

Ethnic differences in metabolite signatures and type 2 diabetes: a nested case–control analysis among people of South Asian, African and European origin

van Valkengoed, Irene G. M., Argmann, Carmen, Ghauharali-van der Vlugt, Karen, Aerts, Johannes M. F. G., Brewster, Lizzy M., Peters, R. J. G., Vaz, Frédéric M., Houtkooper, Riekelt H.

Journal:

Nutrition and Diabetes

Year:

2017

Language:

english

File:

PDF, 304 KB

english, 2017

37

Increased cardiac fatty acid oxidation in a mouse model with decreased malonyl-CoA sensitivity of CPT1B

van Weeghel, Michel, Abdurrachim, Desiree, Nederlof, Rianne, Argmann, Carmen A, Houtkooper, Riekelt H, Hagen, Jacob, Nabben, Miranda, Denis, Simone, Ciapaite, Jolita, Kolwicz, Stephen C, Lopaschuk, Ga

Journal:

Cardiovascular Research

Year:

2018

Language:

english

File:

PDF, 4.18 MB

english, 2018

38

Label-Free LC-MSe in Tissue and Serum Reveals Protein Networks Underlying Differences between Benign and Malignant Serous Ovarian Tumors

Wegdam, Wouter, Argmann, Carmen A., Kramer, Gertjan, Vissers, Johannes P., Buist, Marrije R., Kenter, Gemma G., Aerts, Johannes M. F. G., Meijer, Danielle, Moerland, Perry D., Rota, Rossella

Journal:

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

39

High Throughput Identification of Plasma Proteomic Signature of Inflammatory Bowel Disease

Di Narzo, Antonio F, Brodmerkel, Carrie, Telesco, Shannon E, Argmann, Carmen, Peters, Lauren A, Li, Katherine, Kidd, Brian, Dudley, Joel, Cho, Judy, Schadt, Eric E, Kasarskis, Andrew, Dobrin, Radu, Ha

Journal:

Journal of Crohn's and Colitis

Year:

2018

Language:

english

File:

PDF, 1.08 MB

english, 2018

40

Peroxisomes can oxidize medium- and long-chain fatty acids through a pathway involving ABCD3 and HSD17B4

Violante, Sara, Achetib, Nihad, van Roermund, Carlo W. T., Hagen, Jacob, Dodatko, Tetyana, Vaz, Frédéric M., Waterham, Hans R., Chen, Hongjie, Baes, Myriam, Yu, Chunli, Argmann, Carmen A., Houten, San

Journal:

The FASEB Journal

Year:

2018

Language:

english

File:

PDF, 910 KB

english, 2018

41

Mild inborn errors of metabolism in commonly used inbred mouse strains

Leandro, João, Violante, Sara, Argmann, Carmen A., Hagen, Jacob, Dodatko, Tetyana, Bender, Aaron, Zhang, Wei, Williams, Evan G., Bachmann, Alexis M., Auwerx, Johan, Yu, Chunli, Houten, Sander M.

Journal:

Molecular Genetics and Metabolism

Year:

2019

Language:

english

File:

PDF, 3.35 MB

english, 2019

42

Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies

Ouahed, Jodie, Spencer, Elizabeth, Kotlarz, Daniel, Shouval, Dror S, Kowalik, Matthew, Peng, Kaiyue, Field, Michael, Grushkin-Lerner, Leslie, Pai, Sung-Yun, Bousvaros, Athos, Cho, Judy, Argmann, Carme

Journal:

Inflammatory Bowel Diseases

Year:

2019

File:

PDF, 387 KB

2019

43

P092 Pathogenic B-cell response in ulcerative colitis that associates with treatment resistance and disease complications

Uzzan, M, Martin, J, Keningsberg, E, Castro-Dopico, T, Huang, R, Ungaro, R, Cohen, B, Rahman, A, Rosenstein, A, Gurunathan, S, Dubinsky, M, Clatworthy, M, Suarez-Farinas, M, Argmann, C, Colombel, J F,

Journal:

Journal of Crohn's and Colitis

Year:

2020

File:

PDF, 596 KB

2020